Front Cardiovasc Med. 2026 Jul 15;13:1663802. doi: 10.3389/fcvm.2026.1663802. eCollection 2026.
ABSTRACT
Light chain cardiac amyloidosis (AL-CA) is a severe and progressively infiltrative disease caused by the deposition of misfolded monoclonal immunoglobulin light chains in the myocardial extracellular space. It is associated with poor prognosis and typically presents as diastolic heart failure, arrhythmias, and atrial appendage thrombosis. We report a case of light chain cardiac amyloidosis with bilateral atrial appendage thrombosis. The patient died from refractory heart failure four months after diagnosis.
PMID:42528987 | PMC:PMC13415510 | DOI:10.3389/fcvm.2026.1663802