Rev Cardiovasc Med. 2026 Aug 18;27(8):52871. doi: 10.31083/RCM52871. eCollection 2026 Aug.ABSTRACTArrhythmogenic cardiomyopathy (ACM) is highly sensitive to environmental influences, with physical exercise emerging as one of the most important determinants of disease expression. Growing evidence ind
No abstractEur Heart J. 2026 Aug 30:ehag694. doi: 10.1093/eurheartj/ehag694. Online ahead of print.NO ABSTRACTPMID:42669127 | DOI:10.1093/eurheartj/ehag694
Stem Cell Res. 2026 Sep;95:104054. doi: 10.1016/j.scr.2026.104054. Epub 2026 Jun 30.ABSTRACTWe have established an iPSC cell line carrying mutations in Plakophillin 2 (PKP2) and the A-kinase anchor protein 9 (AKAP9). Plakophilin 2 is an important protein of desmosomes, facilitating cell attachment a
Circ Arrhythm Electrophysiol. 2026 Aug;19(8):e014420. doi: 10.1161/CIRCEP.125.014420. Epub 2026 Jul 2.ABSTRACTBACKGROUND: Current guidelines recommend regular screening for first-degree relatives of gene-elusive arrhythmogenic right ventricular cardiomyopathy (ARVC) patients using a similar regimen
Int J Cardiol. 2026 Oct 15;461:134645. doi: 10.1016/j.ijcard.2026.134645. Epub 2026 Jun 29.ABSTRACTBACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is a genetic heart muscle disease primarily associated with life-threatening ventricular arrhythmias. Improved arrhythmic risk stratification and therapi
Am J Physiol Heart Circ Physiol. 2026 Aug 1;331(2):H440-H452. doi: 10.1152/ajpheart.00368.2026. Epub 2026 Jun 27.ABSTRACTPathogenic variants in desmoglein-2 (DSG2) are a major cause of arrhythmogenic cardiomyopathy (ACM), a disease plagued by ventricular arrhythmias, contractile dysfunction, myocard
Genes (Basel). 2026 Jun 22;17(6):725. doi: 10.3390/genes17060725.ABSTRACTArrhythmogenic cardiomyopathy (ACM/ARVC) is an inherited myocardial disease characterized by progressive fibro-fatty replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death. In addition to mutations
Syst Rev. 2026 Jun 26;15(1):249. doi: 10.1186/s13643-026-03246-2.ABSTRACTHypertrophic cardiomyopathy (HCM), arrhythmogenic cardiomyopathy (ACM) and dilated cardiomyopathy (DCM) represent the most frequent structural heart disorders. Due to the complexity of their diagnosis and the frequent occurrenc
J Transl Med. 2026 Jun 20;24(1):1141. doi: 10.1186/s12967-026-08496-1.ABSTRACTBACKGROUND: Splice-altering variants (SAVs), particularly those outside canonical splice sites, are an underappreciated contributor to inherited cardiovascular diseases. In arrhythmogenic cardiomyopathy (ACM), these varian
Circ Arrhythm Electrophysiol. 2026 Jul;19(7):e014877. doi: 10.1161/CIRCEP.125.014877. Epub 2026 Jun 17.ABSTRACTBACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is a major cause of sudden cardiac death (SCD) in competitive athletes. We aimed to evaluate the prevalence and characteristics of ACM with t
Folia Med Cracov. 2026 Mar 31;66(1):95-102. doi: 10.24425/fmc.2026.158988.ABSTRACTArrhythmogenic right ventricular cardiomyopathy, commonly detected between the second and fifth decades of life, is caused by mutations that result in the dysfunction of the junctions between cardiomyocytes. However, i
Circ Heart Fail. 2026 Jul;19(7):e013966. doi: 10.1161/CIRCHEARTFAILURE.125.013966. Epub 2026 Jun 5.ABSTRACTBACKGROUND: Arrhythmogenic cardiomyopathy (ACM) is an inherited disease that is characterized by lethal ventricular arrhythmias stemming from myocyte dysfunction. ACM is associated with conside
ESC Heart Fail. 2026 May 5;13(3):xvag163. doi: 10.1093/eschf/xvag163.ABSTRACTAIMS: To quantify central oxygen delivery (O2D), peripheral oxygen extraction, and muscle diffusive oxygen conductance (DmO2) during upper-extremity resistance and lower-extremity aerobic exercise in patients with arrhythmo
Children (Basel). 2026 May 12;13(5):669. doi: 10.3390/children13050669.ABSTRACTBackground: Cardiac channelopathies are rare but potentially life-threatening disorders that may present with syncope or seizure-like episodes in children, often leading to misdiagnosis and delayed recognition. Other arrh
Cells. 2026 May 9;15(10):868. doi: 10.3390/cells15100868.ABSTRACTArrhythmogenic cardiomyopathy (ACM) is a genetic myocardial disorder marked by progressive cardiomyocyte loss, fibro-fatty replacement, ventricular arrhythmias, and risk of sudden cardiac death. Traditionally considered a structural an
J Vet Cardiol. 2026 Aug;66:31-40. doi: 10.1016/j.jvc.2026.04.002. Epub 2026 Apr 16.ABSTRACTINTRODUCTION/OBJECTIVE: The aim of this study was to evaluate whether circulating anti-desmoglein-2 antibodies distinguish Boxer dogs with arrhythmogenic right ventricular cardiomyopathy from screened controls
J Am Heart Assoc. 2026 May 5;15(9):e047447. doi: 10.1161/JAHA.125.047447. Epub 2026 Apr 28.ABSTRACTBACKGROUND: Pathogenic variants in PKP2 are the most common cause of familial arrhythmogenic right ventricular cardiomyopathy. This study tests whether plakophilin-2 (PKP2) deficiency only in cardiomyo
Open Heart. 2026 Mar 31;13(1):e003750. doi: 10.1136/openhrt-2025-003750.ABSTRACTBACKGROUND: Truncating variants in the titin gene (TTNtv) are associated with cardiomyopathy, mainly dilated cardiomyopathy (DCM). The clinical presentation and outcomes of arrhythmogenic phenotypes in these patients are
JACC Clin Electrophysiol. 2026 Aug;12(8):1833-1842. doi: 10.1016/j.jacep.2026.02.019. Epub 2026 Mar 16.ABSTRACTBACKGROUND: The ring-like pattern of late gadolinium enhancement (RL-LGE) on cardiac magnetic resonance (CMR) has been proposed as a distinctive imaging marker of arrhythmogenic cardiomyopa
Medicine (Baltimore). 2026 Mar 6;105(10):e47481. doi: 10.1097/MD.0000000000047481.ABSTRACTRATIONALE: Arrhythmogenic left ventricular cardiomyopathy (ALVC) is an arrhythmogenic cardiomyopathy characterized by nonischemic left-ventricular scar, ventricular arrhythmias, and risk of sudden cardiac death
Cureus. 2026 Jan 29;18(1):e102553. doi: 10.7759/cureus.102553. eCollection 2026 Jan.ABSTRACTPediatric ischemic stroke is an uncommon but serious neurological condition with highly variable etiologies. Cerebellar infarctions are particularly rare in children and often present with nonspecific symptom
Circ Arrhythm Electrophysiol. 2026 Feb;19(2):e014265. doi: 10.1161/CIRCEP.125.014265. Epub 2026 Jan 29.ABSTRACTBACKGROUND: The arrhythmogenic right ventricular cardiomyopathy (ARVC) risk calculator estimates the risk of incident sustained ventricular arrhythmia (VA) and performs well in ARVC populat
Zool Res. 2026 Jan 18;47(1):139-154. doi: 10.24272/j.issn.2095-8137.2025.044.ABSTRACTArrhythmogenic cardiomyopathy (ACM) confers elevated risk of ventricular arrhythmias and sudden cardiac death, yet limitations in early lesion sampling and model development continue to hinder mechanistic and transl
BMC Med Imaging. 2026 Jan 28;26(1):102. doi: 10.1186/s12880-026-02172-y.ABSTRACTBACKGROUND: The importance of right atrial (RA) function assessment in arrhythmogenic right ventricular cardiomyopathy (ARVC) is increasingly being recognized. MR-feature tracking (MR-FT) has emerged as a novel approach
