Ramon Brugada il 19/09/2026

Genetic Determinants of Inherited Cardiac Arrhythmias

Methodist Debakey Cardiovasc J. 2026 Sep 15;22(4):78-86. doi: 10.14797/mdcvj.1827. eCollection 2026.ABSTRACTInherited cardiac arrhythmias are a major cause of sudden cardiac death in individuals without structural heart disease. These conditions are primarily genetic, resulting from pathogenic varia

Scott R Coutts il 10/09/2026

Management of Brugada storm in a district general hospital

Br J Cardiol. 2026 Aug 4;33(3):039. doi: 10.5837/bjc.2026.039. eCollection 2026.ABSTRACTA 61-year-old man with Brugada syndrome (BrS) (SCN5A mutation) presented with chest pain to a district general hospital (DGH). There was no history of syncope or ventricular arrhythmias. A subcutaneous implantabl

Mayank Sardana il 26/08/2026

Paediatric-to-adult transition in inherited arrhythmia syndromes

Eur Heart J. 2026 Aug 26:ehag610. doi: 10.1093/eurheartj/ehag610. Online ahead of print.ABSTRACTInherited arrhythmia syndromes (IAS)-including long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), and Brugada syndrome (BrS)-are important causes of sudden cardiac deat

Elisabet Selga il 10/08/2026

Generation of human induced pluripotent stem cell lines from relatives of an unexplained sudden cardiac death victim carrying a Brugada Syndrome-associated, SCN5A c.287 T > C, variant

Stem Cell Res. 2026 Sep;95:104071. doi: 10.1016/j.scr.2026.104071. Epub 2026 Aug 2.ABSTRACTPatient-derived induced pluripotent stem cells (hiPSC) are a valuable approach to model cardiovascular diseases. We nucleofected non-integrating episomal vectors in skin fibroblasts of four family members. Two

Ian R Sigal il 16/07/2026

Cardiac Arrest in a Young Soccer Player With a Pathogenic SCN5A Variant

JACC Case Rep. 2026 Jul 15;31(28):108906. doi: 10.1016/j.jaccas.2026.108906.ABSTRACTBACKGROUND: The SCN5A gene encodes the alpha subunit of the cardiac sodium channel; variants are associated with inherited cardiac diseases including long QT syndrome, sick sinus syndrome, dilated cardiomyopathy, arr