J Clin Med. 2026 May 19;15(10):3903. doi: 10.3390/jcm15103903.ABSTRACTThis paper intends to go through the medical history of a new syndrome, beginning from its incidental observation to the nowadays ongoing reports quickly approaching 7000 published papers. This large number makes it difficult for
Children (Basel). 2026 May 12;13(5):669. doi: 10.3390/children13050669.ABSTRACTBackground: Cardiac channelopathies are rare but potentially life-threatening disorders that may present with syncope or seizure-like episodes in children, often leading to misdiagnosis and delayed recognition. Other arrh
Children (Basel). 2026 May 8;13(5):659. doi: 10.3390/children13050659.ABSTRACTBACKGROUND: Channelopathies represent a heterogeneous group of rare inherited cardiac diseases associated with life-threatening arrhythmias. Our knowledge of their epidemiology in childhood is limited. The aim of this stud
Biomedicines. 2026 May 12;14(5):1094. doi: 10.3390/biomedicines14051094.ABSTRACTBackground: Brugada Syndrome (BrS) is a cardiac arrhythmia associated with an increased risk of ventricular arrhythmias and sudden cardiac arrest. Although the arrhythmic substrate is traditionally localized to the ventr
No abstractHeartRhythm Case Rep. 2026 Feb 26;12(5):572-573. doi: 10.1016/j.hrcr.2026.02.014. eCollection 2026 May.NO ABSTRACTPMID:42181124 | PMC:PMC13198343 | DOI:10.1016/j.hrcr.2026.02.014
No abstractHeartRhythm Case Rep. 2026 Feb 28;12(5):571-572. doi: 10.1016/j.hrcr.2026.01.029. eCollection 2026 May.NO ABSTRACTPMID:42181119 | PMC:PMC13198312 | DOI:10.1016/j.hrcr.2026.01.029
JACC Case Rep. 2026 May 20;31(20):108237. doi: 10.1016/j.jaccas.2026.108237.ABSTRACTBACKGROUND: Epicardial ablation for Brugada syndrome targeting abnormal right ventricular outflow tract (RVOT) substrate with local abnormal ventricular activity (LAVA) demonstrated efficacy in European trials but re
JACC Case Rep. 2026 May 20;31(20):107960. doi: 10.1016/j.jaccas.2026.107960.ABSTRACTBrugada syndrome is classically characterized by coved-type ST-segment elevation in leads V1 or V2. Repolarization abnormalities in peripheral leads have been previously reported in patients with Brugada syndrome; ho
JACC Case Rep. 2026 May 20;31(20):107620. doi: 10.1016/j.jaccas.2026.107620.ABSTRACTCASE SUMMARY: We describe the case of a 21-year-old man with severe traumatic brain injury requiring prolonged sedation and vasopressor support, subsequently developing a sudden broad-complex sinusoidal rhythm, and d
JACC Case Rep. 2026 May 20;31(20):107364. doi: 10.1016/j.jaccas.2026.107364. Epub 2026 Mar 16.ABSTRACTBACKGROUND: Brugada phenocopy is a reversible Brugada pattern on an electrocardiogram (ECG) caused by identifiable clinical conditions (such as fever, electrolyte abnormalities, or drug exposure) in
Am J Physiol Heart Circ Physiol. 2026 May 15. doi: 10.1152/ajpheart.00093.2026. Online ahead of print.ABSTRACTDifferent modes of onset of ventricular arrhythmias (VA), preceded by characteristic electrocardiogram patterns, have been observed in patients with J-wave syndromes (JWS), including Brugada
Int J Mol Sci. 2026 Apr 28;27(9):3900. doi: 10.3390/ijms27093900.ABSTRACTBrugada syndrome (BrS) is a rare but potentially life-threatening condition that may lead to sudden cardiac death. Among the causes, dysfunctions of ion channels involved in the cardiac action potential (specifically in SCN5A a
No abstractHeart Rhythm. 2026 May 5:S1547-5271(26)02341-6. doi: 10.1016/j.hrthm.2026.03.1969. Online ahead of print.NO ABSTRACTPMID:42097252 | DOI:10.1016/j.hrthm.2026.03.1969
No abstractHeart Rhythm. 2026 May 5:S1547-5271(26)02350-7. doi: 10.1016/j.hrthm.2026.04.060. Online ahead of print.NO ABSTRACTPMID:42097248 | DOI:10.1016/j.hrthm.2026.04.060
No abstractEuropace. 2026 May 6;28(5):euag098. doi: 10.1093/europace/euag098.NO ABSTRACTPMID:42090354 | PMC:PMC13148240 | DOI:10.1093/europace/euag098
JACC Case Rep. 2026 May 27;31(21):108014. doi: 10.1016/j.jaccas.2026.108014. Epub 2026 Apr 22.ABSTRACTCASE SUMMARY: We describe the case of an 88-year-old male patient referred to our cardiology outpatient clinic because of recent and recurrent syncopal episodes, often preceded by palpitations. At c
JACC Case Rep. 2026 May 27;31(21):107843. doi: 10.1016/j.jaccas.2026.107843. Epub 2026 Apr 20.ABSTRACTBACKGROUND: Brugada syndrome (BrS), traditionally associated with ventricular arrhythmic risk, may also involve conduction disturbances. SCN5A deleterious variants predispose to bradyarrhythmias and
AME Case Rep. 2026 Feb 2;10:56. doi: 10.21037/acr-2025-275. eCollection 2026.ABSTRACTBACKGROUND: Brugada syndrome (BrS) is an inherited cardiac channelopathy associated with a predisposition to malignant ventricular arrhythmias and sudden cardiac death (SCD). It demonstrates a notably higher prevale
JACC Case Rep. 2026 May 6;31(18):107528. doi: 10.1016/j.jaccas.2026.107528. Epub 2026 Mar 31.ABSTRACTBACKGROUND: Brugada syndrome (BrS) and arrhythmogenic cardiomyopathy (ACM) may overlap clinically, but shared mechanisms remain unclear. RYR1 mutations have not been previously linked to these arrhyt
Cureus. 2026 Feb 24;18(2):e104174. doi: 10.7759/cureus.104174. eCollection 2026 Feb.ABSTRACTSudden cardiac death in athletes, though uncommon, remains a major concern in sports cardiology. Many responsible cardiovascular conditions, including cardiomyopathies, inherited channelopathies, valvular dis
Eur Heart J Case Rep. 2026 Mar 10;10(3):ytag176. doi: 10.1093/ehjcr/ytag176. eCollection 2026 Mar.ABSTRACTBACKGROUND: Oxymetazoline nasal spray is a widely used over-the-counter sympathomimetic decongestant. While generally safe at therapeutic doses, overdose can result in systemic vasoconstriction
Biomedicines. 2026 Mar 5;14(3):582. doi: 10.3390/biomedicines14030582.ABSTRACTBackground: Brugada syndrome (BrS) is a genetic cardiac arrhythmia disorder inherited in an autosomal dominant manner, characterized by ST-segment elevation in the right precordial leads (V1-V3) on electrocardiograms (ECGs
Circ Res. 2026 Apr 24;138(9):e328159. doi: 10.1161/CIRCRESAHA.125.328159. Epub 2026 Mar 25.ABSTRACTBACKGROUND: NaV (voltage-gated sodium) channels drive cardiac excitability. Although NaV1.5 is the primary cardiac isoform, the composition and functional contributions of non-NaV1.5 isoforms in the he
Cureus. 2026 Feb 20;18(2):e103952. doi: 10.7759/cureus.103952. eCollection 2026 Feb.ABSTRACTBrugada syndrome is an inherited cardiac channelopathy associated with life-threatening ventricular arrhythmias and sudden cardiac death and is often detected incidentally. We report a 48-year-old Filipino ma
