No abstractHeartRhythm Case Rep. 2025 Oct 9;11(12):1343-1348. doi: 10.1016/j.hrcr.2025.09.015. eCollection 2025 Dec.NO ABSTRACTPMID:41550241 | PMC:PMC12805269 | DOI:10.1016/j.hrcr.2025.09.015
No abstractHeartRhythm Case Rep. 2025 Sep 18;11(12):1309-1314. doi: 10.1016/j.hrcr.2025.09.006. eCollection 2025 Dec.NO ABSTRACTPMID:41550211 | PMC:PMC12805295 | DOI:10.1016/j.hrcr.2025.09.006
Stem Cell Res. 2026 Jan 8;91:103910. doi: 10.1016/j.scr.2026.103910. Online ahead of print.ABSTRACTThe GPD1L gene is located on 3p22.3. It encodes the glycerol phosphate dehydrogenase 1-like protein with homology to glycerol phosphate dehydrogenase (GPD1L), but the function of this enzyme is unclear
Eur Heart J Case Rep. 2025 Dec 12;10(1):ytaf640. doi: 10.1093/ehjcr/ytaf640. eCollection 2026 Jan.ABSTRACTBACKGROUND: Brugada syndrome (BrS) is a rare cardiovascular condition that can lead to life-threatening arrhythmias. The SCN5A gene, most implicated in heritable BrS, is found in only 20% of tho
BMC Anesthesiol. 2026 Jan 13. doi: 10.1186/s12871-025-03600-2. Online ahead of print.ABSTRACTBACKGROUND: Brugada syndrome occurs typically without structural heart disease and is regarded as an autosomal dominant condition. It is linked to a range of cardiac symptoms as well as potentially fatal ven
Egypt Heart J. 2026 Jan 12;78(1):4. doi: 10.1186/s43044-026-00714-x.ABSTRACTBACKGROUND: This cross-sectional study with limited prospective cohort follow-up aimed to determine the prevalence of Brugada-type ECG patterns (BTEPs) among asymptomatic Upper Egyptians using standard and high precordial le
Medicine (Baltimore). 2025 Dec 26;104(52):e46907. doi: 10.1097/MD.0000000000046907.ABSTRACTRATIONALE: Coronavirus disease 2019 (COVID-19) can cause electrocardiographic changes, such as ST-segment elevation, by increasing the dispersion of cardiac repolarization or cause delayed depolarization in a
Genes (Basel). 2025 Dec 3;16(12):1448. doi: 10.3390/genes16121448.ABSTRACTInherited arrhythmias and cardiomyopathies are a group of potentially lethal genetic cardiac disorders which are often passed down through generations and pose risks to several family members. While individually rare, these co
Front Cardiovasc Med. 2025 Dec 12;12:1722105. doi: 10.3389/fcvm.2025.1722105. eCollection 2025.ABSTRACTBrugada syndrome (BrS) is an inherited arrhythmia disorder and a major cause of sudden cardiac death below 50 years. Despite more than three decades of research, diagnosis and risk prediction remai
CONCLUSION: We have uncovered a new genetic basis for LQTS. Our findings demonstrate that the MOG1^(L18F) variant impairs AV conduction, increases I(NaL), opposes repolarizing currents, and prolongs both action potential duration and the QT interval, ultimately leading to ventricular arrhythmias, pa
No abstractCJC Open. 2025 Aug 26;7(11):1463-1465. doi: 10.1016/j.cjco.2025.08.005. eCollection 2025 Nov.NO ABSTRACTPMID:41425786 | PMC:PMC12713172 | DOI:10.1016/j.cjco.2025.08.005
Open Heart. 2025 Dec 18;12(2):e003119. doi: 10.1136/openhrt-2024-003119.ABSTRACTINTRODUCTION AND OBJECTIVES: Brugada syndrome (BS) is a channelopathy associated with an increased risk of sudden cardiac death (SCD). Intense physical activity is a recognised trigger of life-threatening arrhythmias in
Diagnostics (Basel). 2025 Nov 21;15(23):2956. doi: 10.3390/diagnostics15232956.ABSTRACTPectus excavatum (PE) is the most frequent chest wall deformity, representing 65-95% of all cases, with an estimated prevalence of up to 1 in 300 births. Despite its frequency, it remains underrecognized in sports
World J Transplant. 2025 Dec 18;15(4):107839. doi: 10.5500/wjt.v15.i4.107839.ABSTRACTBACKGROUND: Brugada syndrome (BS) is a rare disorder affecting approximately 5 in every 10000 people. Reports of kidney donation in individuals with BS are exceptionally uncommon.CASE SUMMARY: The decision to permit
Rev Cardiovasc Med. 2025 Nov 11;26(11):43820. doi: 10.31083/RCM43820. eCollection 2025 Nov.ABSTRACTBrugada syndrome (BrS) is an inherited cardiac arrhythmia disorder associated with sudden cardiac death (SCD), primarily due to ventricular tachycardia (VT) or ventricular fibrillation (VF). Meanwhile,
Ann Noninvasive Electrocardiol. 2026 Jan;31(1):e70137. doi: 10.1111/anec.70137.ABSTRACTBACKGROUND: Ajmaline challenge (AC) is used for diagnosing suspected Brugada syndrome (BS) in patients with unexplained syncope, survived cardiac arrest, or for family screening.PURPOSE: To evaluate baseline ECG m
No abstractHeartRhythm Case Rep. 2025 Jul 3;11(9):958-961. doi: 10.1016/j.hrcr.2025.06.031. eCollection 2025 Sep.NO ABSTRACTPMID:41333925 | PMC:PMC12666971 | DOI:10.1016/j.hrcr.2025.06.031
Res Sq [Preprint]. 2025 Nov 17:rs.3.rs-8058536. doi: 10.21203/rs.3.rs-8058536/v1.ABSTRACTTimothy Syndrome is a multisystemic genetic disorder, classically characterised by prolonged QT interval and subsequent cardiac arrhythmias, neurodevelopmental disorders including developmental delay and autism,
Eur J Pediatr. 2025 Dec 3;184(12):815. doi: 10.1007/s00431-025-06646-z.ABSTRACTInherited arrhythmogenic diseases (IADs), such as long QT syndrome (LQTS), Brugada syndrome (BrS), arrhythmogenic right ventricular cardiomyopathy (ARVC), catecholaminergic polymorphic ventricular tachycardia (CPVT) and l
JACC Case Rep. 2026 Jan 21;31(3):106241. doi: 10.1016/j.jaccas.2025.106241. Epub 2025 Dec 2.ABSTRACTBACKGROUND: The role of quinidine in patients with early repolarization syndrome (ERS) is known, but it is not available in many countries. We share our experience with quinine sulfate in the suppress
Medicine (Baltimore). 2025 Nov 28;104(48):e46181. doi: 10.1097/MD.0000000000046181.ABSTRACTRATIONALE: Brugada syndrome (BrS) is a rare and life-threatening cardiac electrophysiological disease, characterized by typical electrocardiogram changes and malignant arrhythmia, which is easy to induce sudde
Stem Cell Res Ther. 2025 Dec 1;16(1):670. doi: 10.1186/s13287-025-04793-6.ABSTRACTBACKGROUND: Fever or inflammation state may enhance the Brugada syndrome (BrS) phenotype in some but not all patients. However, the underlying mechanism in human cardiomyocytes has not yet been clarified.METHODS: Human
Commun Biol. 2025 Nov 28;8(1):1854. doi: 10.1038/s42003-025-09296-x.ABSTRACTBrugada syndrome (BrS) is an inherited cardiac arrhythmic disorder associated with an increased risk of malignant ventricular arrhythmia and sudden death. Mendelian randomisation implicated N-palmitoyl glycine (PalGly) in Br
Stem Cell Res. 2025 Dec;89:103875. doi: 10.1016/j.scr.2025.103875. Epub 2025 Nov 25.ABSTRACTUp to 40 % of genetic variants identified in inherited arrhythmia syndromes (IAS) are classified as variants of uncertain significance (VUS) due to limited clinical and functional evidence. In Brugada syndrom
