Sante Ment Que. 2026 Spring;51(1):63-78.ABSTRACTClozapine is the gold-standard treatment for refractory psychotic disorders but is associated with rare, potentially fatal cardiovascular complications. We report the case of a 72-year-old man with schizoaffective disorder and complex multimorbidity wh
No abstractHeartRhythm Case Rep. 2026 Apr 9;12(7):749-751. doi: 10.1016/j.hrcr.2026.04.003. eCollection 2026 Jul.NO ABSTRACTPMID:42472196 | PMC:PMC13379336 | DOI:10.1016/j.hrcr.2026.04.003
medRxiv [Preprint]. 2026 Jul 10:2026.07.07.26356386. doi: 10.64898/2026.07.07.26356386.ABSTRACTBrugada syndrome (BrS) is an inherited cardiac condition characterized by a hallmark ECG pattern and an increased risk of sudden cardiac death. Central to the aetiology of BrS, the SCN5A region harbours bo
JACC Case Rep. 2026 Jul 15;31(28):108906. doi: 10.1016/j.jaccas.2026.108906.ABSTRACTBACKGROUND: The SCN5A gene encodes the alpha subunit of the cardiac sodium channel; variants are associated with inherited cardiac diseases including long QT syndrome, sick sinus syndrome, dilated cardiomyopathy, arr
Biomed Res Int. 2026;2026(1):e4900599. doi: 10.1155/bmri/4900599.ABSTRACTBrugada syndrome (BrS) is a rare but potentially fatal genetic cardiac disorder, primarily caused by mutations in sodium and potassium ion channels, leading to ventricular arrhythmias and sudden cardiac death. Despite advances
Clin Pract Cases Emerg Med. 2025 Aug;9(3):274-277. doi: 10.5811/cpcem.1573.ABSTRACTINTRODUCTION: Brugada syndrome, a cardiac channelopathy, manifests with ventricular arrhythmia. Diagnosis relies on a type 1 Brugada electrocardiogram (ECG) pattern, while type 2 and type 3 patterns may necessitate el
Clin Pract Cases Emerg Med. 2025 Aug;9(3):326-328. doi: 10.5811/cpcem.47005.ABSTRACTINTRODUCTION: Brugada syndrome is a ventricular arrhythmia and type of sodium channelopathy that can be seen in the absence of structural heart disease. Recognition of this pattern on electrocardiogram (ECG) is impor
No abstractFront Cardiovasc Med. 2026 Jun 29;13:1851845. doi: 10.3389/fcvm.2026.1851845. eCollection 2026.NO ABSTRACTPMID:42445531 | PMC:PMC13357221 | DOI:10.3389/fcvm.2026.1851845
Korean Circ J. 2026 Jun 2. doi: 10.4070/kcj.2025.0547. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: The electrocardiography (ECG) morphology of lead aVR has been associated with arrhythmic risk in Brugada syndrome, but its role in arrhythmogenic right ventricular cardiomyopathy (ARVC) re
Clin Case Rep. 2026 Jul 1;14(7):e73081. doi: 10.1002/ccr3.73081. eCollection 2026 Jul.ABSTRACTTransvalvular device leads are undesirable following tricuspid valve replacement. Simultaneous lead extraction and intra-operative EV-ICD implantation can provide ongoing defibrillator therapy without cross
Clin Case Rep. 2026 Jun 23;14(7):e73042. doi: 10.1002/ccr3.73042. eCollection 2026 Jul.ABSTRACTAlthough Brugada syndrome has traditionally been considered a primary electrical disease, accumulating evidence supports the presence of subtle structural abnormalities, particularly involving the right ve
JACC Case Rep. 2026 Jun 25:108999. doi: 10.1016/j.jaccas.2026.108999. Online ahead of print.ABSTRACTA 67-year-old man with recurrent syncope and chronic right bundle branch block underwent left bundle branch pacing for infra-Hisian atrioventricular block. Because a prior electrocardiogram showed a t
Comput Biol Med. 2026 Aug 15;213:111816. doi: 10.1016/j.compbiomed.2026.111816. Epub 2026 Jun 22.ABSTRACTElectrocardiogram (ECG) interpretation is fundamental for cardiac diagnosis. Machine learning has proven strong performance in ECG analysis but models often face challenges when deployed in real-
Heart Int. 2026 Jun 2;20(1):20-34. doi: 10.17925/HI.2026.20.1.3. eCollection 2026.ABSTRACTBACKGROUND: Sudden cardiac arrest (SCA) in young adults (18-40 years) is rare but devastating, often occurring without prior symptoms. It often occurs in the absence of preceding symptoms or known structural he
J Arrhythm. 2026 Jun 11;42(3):e70391. doi: 10.1002/joa3.70391. eCollection 2026 Jun.ABSTRACTSubcutaneous-to-extravascular implantable cardioverter-defibrillator exchange can create a practical challenge: the existing subcutaneous generator pocket lies posteriorly, whereas the new extravascular gener
Diagnostics (Basel). 2026 Jun 3;16(11):1718. doi: 10.3390/diagnostics16111718.ABSTRACTBackground/Objectives: The Type 1 Brugada ECG pattern (BrP1) fluctuates according to autonomic influences. Tilt table testing induces changes in both sympathetic and parasympathetic activity. It may provide insight
No abstractHeart Rhythm. 2026 Jun 10:S1547-5271(26)02467-7. doi: 10.1016/j.hrthm.2026.05.058. Online ahead of print.NO ABSTRACTPMID:42269999 | DOI:10.1016/j.hrthm.2026.05.058
West J Emerg Med. 2026 Apr 2;27(3):597-604. doi: 10.5811/westjem.48718.ABSTRACTBACKGROUND: Artificial intelligence (AI) tools are increasingly being explored for medical applications; however, their effectiveness in emergency electrocardiogram (ECG) interpretation is under-investigated. In this pilo
Brugada syndrome is a cardiac channelopathy associated with sudden cardiac death caused by ventricular arrhythmias. Although pharmacologic Na^(+) channel blocker testing remains central to diagnosis, the role of exercise stress testing (EST) in Brugada syndrome is increasingly recognized. Evidence i
No abstractEur J Anaesthesiol. 2026 Jul 1;43(7):636-637. doi: 10.1097/EJA.0000000000002430. Epub 2026 Jun 10.NO ABSTRACTPMID:42231770 | PMC:PMC13261815 | DOI:10.1097/EJA.0000000000002430
Chin J Traumatol. 2026 May 19:S1008-1275(26)00102-1. doi: 10.1016/j.cjtee.2026.04.004. Online ahead of print.ABSTRACTBrugada syndrome, a rare cardiac disorder stemming from mutations in sodium channels, manifests as ventricular arrhythmias, potentially culminating in sudden cardiac death. This case
World J Clin Pediatr. 2026 Jun 9;15(2):114189. doi: 10.5409/wjcp.v15.i2.114189. eCollection 2026 Jun 9.ABSTRACTTRPM4 is a member of transient receptor potential (TRP) ion channel group which greatly contributes to cardiomyocyte function and physiology. It controls the dynamic stabilization of calciu
Cureus. 2026 Apr 26;18(4):e107754. doi: 10.7759/cureus.107754. eCollection 2026 Apr.ABSTRACTBrugada phenocopies are clinical entities characterized by electrocardiographic patterns identical to those of congenital Brugada syndrome but occurring in the context of identifiable, reversible underlying c
No abstractEuropace. 2026 Jun 2;28(6):euag131. doi: 10.1093/europace/euag131.NO ABSTRACTPMID:42198895 | PMC:PMC13256013 | DOI:10.1093/europace/euag131
