No abstractHeart Rhythm O2. 2026 May 9;7(8):1583-1587. doi: 10.1016/j.hroo.2026.05.001. eCollection 2026 Aug.NO ABSTRACTPMID:42666638 | PMC:PMC13523568 | DOI:10.1016/j.hroo.2026.05.001
Genes (Basel). 2026 Jul 29;17(8):885. doi: 10.3390/genes17080885.ABSTRACTLong QT Syndrome type 2 (LQT2) and Brugada syndrome are inherited cardiac channelopathies that predispose affected individuals to ventricular arrhythmias and sudden cardiac death. We report the case of a 15-year-old male carryi
Clin Pract Cases Emerg Med. 2026 Aug;10(3):262-265. doi: 10.5811/cpcem.52845.ABSTRACTINTRODUCTION: Brugada syndrome is an important differential diagnosis for unexplained sudden cardiac arrest, particularly in younger patients. The electrocardiographic (ECG) pattern characteristic of Brugada syndrom
No abstractEur Heart J. 2026 Aug 26:ehag652. doi: 10.1093/eurheartj/ehag652. Online ahead of print.NO ABSTRACTPMID:42643111 | DOI:10.1093/eurheartj/ehag652
Eur Heart J. 2026 Aug 26:ehag610. doi: 10.1093/eurheartj/ehag610. Online ahead of print.ABSTRACTInherited arrhythmia syndromes (IAS)-including long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), and Brugada syndrome (BrS)-are important causes of sudden cardiac deat
No abstractHeartRhythm Case Rep. 2026 Jun 11;12(8):970-976. doi: 10.1016/j.hrcr.2026.06.004. eCollection 2026 Aug.NO ABSTRACTPMID:42626593 | PMC:PMC13492438 | DOI:10.1016/j.hrcr.2026.06.004
No abstractHeartRhythm Case Rep. 2026 Jun 11;12(8):921-925. doi: 10.1016/j.hrcr.2026.05.022. eCollection 2026 Aug.NO ABSTRACTPMID:42626325 | PMC:PMC13492415 | DOI:10.1016/j.hrcr.2026.05.022
Cureus. 2026 Jul 20;18(7):e113017. doi: 10.7759/cureus.113017. eCollection 2026 Jul.ABSTRACTIntroduction Cardiomyopathies (CMs), as well as primary electrical disorders, i.e., inherited arrhythmia syndromes (IAS), including long-QT syndrome, catecholaminergic polymorphic ventricular tachycardia, and
Front Cardiovasc Med. 2026 Jul 30;13:1876080. doi: 10.3389/fcvm.2026.1876080. eCollection 2026.ABSTRACTBACKGROUND: Arrhythmogenic cardiomyopathy (ACM) and Brugada syndrome (BrS) are inherited arrhythmogenic disorders historically defined by their predisposition to ventricular arrhythmias and sudden
The cardiac sodium channel Na(V)1.5, encoded by SCN5A, generates the inward sodium current required for myocardial excitability and impulse conduction. Loss-of-function mutations of Na(V)1.5 have been implicated in inherited arrhythmia syndromes, including Brugada syndrome, progressive cardiac condu
Stem Cell Res. 2026 Sep;95:104071. doi: 10.1016/j.scr.2026.104071. Epub 2026 Aug 2.ABSTRACTPatient-derived induced pluripotent stem cells (hiPSC) are a valuable approach to model cardiovascular diseases. We nucleofected non-integrating episomal vectors in skin fibroblasts of four family members. Two
No abstractArq Bras Cardiol. 2026 Aug 3;123(5):e20260471. doi: 10.36660/abc.20260471. eCollection 2026.NO ABSTRACTPMID:42561307 | PMC:PMC13399058 | DOI:10.36660/abc.20260471
Front Cardiovasc Med. 2026 Jul 22;13:1900085. doi: 10.3389/fcvm.2026.1900085. eCollection 2026.ABSTRACTInherited arrhythmia syndromes-including Brugada syndrome (BrS), long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), and short QT syndrome (SQTS)-can cause malign
Am J Cardiol. 2026 Jul 27;276:11-17. doi: 10.1016/j.amjcard.2026.07.014. Online ahead of print.ABSTRACTBrugada Syndrome (BrS) is a genetic condition that increases the risk of sudden cardiac death. Diagnosis relies on the presence of a type 1 Brugada electrocardiogram (ECG) pattern, which may be int
Sante Ment Que. 2026 Spring;51(1):63-78.ABSTRACTClozapine is the gold-standard treatment for refractory psychotic disorders but is associated with rare, potentially fatal cardiovascular complications. We report the case of a 72-year-old man with schizoaffective disorder and complex multimorbidity wh
No abstractHeartRhythm Case Rep. 2026 Apr 9;12(7):749-751. doi: 10.1016/j.hrcr.2026.04.003. eCollection 2026 Jul.NO ABSTRACTPMID:42472196 | PMC:PMC13379336 | DOI:10.1016/j.hrcr.2026.04.003
medRxiv [Preprint]. 2026 Jul 10:2026.07.07.26356386. doi: 10.64898/2026.07.07.26356386.ABSTRACTBrugada syndrome (BrS) is an inherited cardiac condition characterized by a hallmark ECG pattern and an increased risk of sudden cardiac death. Central to the aetiology of BrS, the SCN5A region harbours bo
Med Res Rev. 2026 Jul 17. doi: 10.1002/med.70077. Online ahead of print.ABSTRACTThe Nav1.5 channel, a major isoform of voltage-gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutat
JACC Case Rep. 2026 Jul 15;31(28):108906. doi: 10.1016/j.jaccas.2026.108906.ABSTRACTBACKGROUND: The SCN5A gene encodes the alpha subunit of the cardiac sodium channel; variants are associated with inherited cardiac diseases including long QT syndrome, sick sinus syndrome, dilated cardiomyopathy, arr
Biomed Res Int. 2026;2026(1):e4900599. doi: 10.1155/bmri/4900599.ABSTRACTBrugada syndrome (BrS) is a rare but potentially fatal genetic cardiac disorder, primarily caused by mutations in sodium and potassium ion channels, leading to ventricular arrhythmias and sudden cardiac death. Despite advances
Clin Pract Cases Emerg Med. 2025 Aug;9(3):274-277. doi: 10.5811/cpcem.1573.ABSTRACTINTRODUCTION: Brugada syndrome, a cardiac channelopathy, manifests with ventricular arrhythmia. Diagnosis relies on a type 1 Brugada electrocardiogram (ECG) pattern, while type 2 and type 3 patterns may necessitate el
Clin Pract Cases Emerg Med. 2025 Aug;9(3):326-328. doi: 10.5811/cpcem.47005.ABSTRACTINTRODUCTION: Brugada syndrome is a ventricular arrhythmia and type of sodium channelopathy that can be seen in the absence of structural heart disease. Recognition of this pattern on electrocardiogram (ECG) is impor
No abstractFront Cardiovasc Med. 2026 Jun 29;13:1851845. doi: 10.3389/fcvm.2026.1851845. eCollection 2026.NO ABSTRACTPMID:42445531 | PMC:PMC13357221 | DOI:10.3389/fcvm.2026.1851845
Korean Circ J. 2026 Jun 2. doi: 10.4070/kcj.2025.0547. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: The electrocardiography (ECG) morphology of lead aVR has been associated with arrhythmic risk in Brugada syndrome, but its role in arrhythmogenic right ventricular cardiomyopathy (ARVC) re
