BMJ Paediatr Open. 2026 Mar 9;10(1):e004403. doi: 10.1136/bmjpo-2025-004403.ABSTRACTOBJECTIVE: To describe the development and utilisation of a paediatric inherited arrhythmia clinic (IAC) from 2014 to 2024, including service developments following the introduction of cardiac genetic coordinators (C
Front Cardiovasc Med. 2026 Feb 19;13:1726536. doi: 10.3389/fcvm.2026.1726536. eCollection 2026.ABSTRACTBrugada syndrome (BrS) is a genetically determined cardiac arrhythmogenic syndrome with increased risk of sudden cardiac death. BrS is mostly caused by mutations in SCN5A gene encoding the primary
JACC Case Rep. 2026 Feb 26:107173. doi: 10.1016/j.jaccas.2026.107173. Online ahead of print.ABSTRACTBACKGROUND: Brugada syndrome is an inherited cardiac channelopathy causing malignant ventricular arrhythmias and sudden death in structurally normal hearts, which may be unmasked by medications or rec
PLOS Digit Health. 2026 Feb 25;5(2):e0001222. doi: 10.1371/journal.pdig.0001222. eCollection 2026 Feb.ABSTRACTDeep neural networks can classify ECGs with high accuracy when training data is abundant. Rare conditions like Brugada syndrome, an inherited arrhythmia syndrome predisposing to sudden death
J Arrhythm. 2026 Feb 20;42(1):e70284. doi: 10.1002/joa3.70284. eCollection 2026 Feb.ABSTRACTJ-wave syndromes (JWS)-comprising Brugada syndrome (BrS) and early repolarization syndrome (ERS)-are important causes of malignant ventricular arrhythmias and sudden cardiac death in patients whose hearts app
JACC Case Rep. 2026 Feb 21:107048. doi: 10.1016/j.jaccas.2026.107048. Online ahead of print.ABSTRACTBACKGROUND: Brugada phenocopy (BrP) denotes reversible Brugada-type electrocardiogram changes from transient triggers, requiring management distinct from congenital Brugada syndrome.CASE SUMMARY: A 19
Front Cardiovasc Med. 2026 Feb 4;13:1754683. doi: 10.3389/fcvm.2026.1754683. eCollection 2026.ABSTRACTOrofacial pain, diagnosed and treated in a subfield of dentistry, highly relies on long-term psychotropic, neuromodulating, and analgesic regimens that have the potential to alter cardiac ion channe
Eur Heart J Case Rep. 2026 Feb 3;10(2):ytag078. doi: 10.1093/ehjcr/ytag078. eCollection 2026 Feb.ABSTRACTBACKGROUND: Abnormal epicardial potentials in J wave syndrome predominantly involve the right ventricular outflow tract (RVOT), while left ventricular (LV) involvement remains less characterized
Front Cardiovasc Med. 2026 Jan 30;12:1715146. doi: 10.3389/fcvm.2025.1715146. eCollection 2025.ABSTRACTBrugada Syndrome (BrS) is a rare but clinically significant inherited arrhythmia disorder characterized by a type 1 ECG pattern and an increased risk of sudden cardiac death (SCD). Since its first
Adv Physiol Educ. 2026 Feb 16. doi: 10.1152/advan.00081.2025. Online ahead of print.ABSTRACTINTRODUCTION: Paramedics in the UK independently assess patients with transient loss of consciousness (TLOC) in community settings. The UK's National Institute for Health and Care Excellence publish guidance
Rev Cardiovasc Med. 2026 Jan 16;27(1):43173. doi: 10.31083/RCM43173. eCollection 2026 Jan.ABSTRACTDespite the relatively low incidence of Brugada syndrome (BrS) globally, the risk of sudden cardiac death remains alarmingly high, reaching rates of up to 28%. According to current clinical guidelines,
JACC Clin Electrophysiol. 2026 Feb 5:S2405-500X(25)01118-1. doi: 10.1016/j.jacep.2025.12.033. Online ahead of print.ABSTRACTBACKGROUND: Loss-of-function mutations in the SCN5A gene, which encodes for the predominant cardiac NaV isoform, NaV1.5, result in either deficiency in the channel expression o
Medicina (B Aires). 2026;86(1):247-250.ABSTRACTBrugada syndrome is a hereditary channelopathy associated with a high risk of sudden cardiac death in young individuals. We present the case of a 25-yearold man with a syncopal episode, without prodromes or defenses, during physical activity and a bilat
Oxf Med Case Reports. 2026 Jan 28;2026(1):omaf301. doi: 10.1093/omcr/omaf301. eCollection 2026 Jan.ABSTRACTINTRODUCTION: Brugada syndrome is a genetic disorder associated with sudden cardiac death (SCD) due to ventricular fibrillation (VF). The diagnosis relies on detecting a Type 1 ST-segment eleva
Int J Mol Sci. 2026 Jan 15;27(2):880. doi: 10.3390/ijms27020880.ABSTRACTDeleterious variants in SCN5A lead to a wide clinical spectrum that includes pathologies characterized by life-threatening cardiac events (CEs). In the pediatric population, early identification, management, and risk stratificat
Circ Arrhythm Electrophysiol. 2026 Feb;19(2):e014270. doi: 10.1161/CIRCEP.125.014270. Epub 2026 Jan 26.ABSTRACTBACKGROUND: Pathogenic SCN5A variants are associated with inherited arrhythmias such as long-QT syndrome, Brugada syndrome, and sick sinus syndrome. While Nav1.5, an α-subunit of the cardia
Rev Port Cardiol. 2026 Mar;45(3):107-115. doi: 10.1016/j.repc.2025.10.006. Epub 2026 Jan 23.ABSTRACTINTRODUCTION AND OBJECTIVES: Implantable cardioverter-defibrillators (ICDs) are among the most effective interventions for the prevention of sudden cardiac death. However, traditional transvenous syst
Eur Heart J Case Rep. 2025 Dec 23;10(1):ytaf673. doi: 10.1093/ehjcr/ytaf673. eCollection 2026 Jan.ABSTRACTBACKGROUND: Brugada syndrome (BrS) is a hereditary arrhythmic disorder associated with an increased risk of ventricular arrhythmias (VA) and sudden cardiac death (SCD). Certain triggers may unma
No abstractHeartRhythm Case Rep. 2025 Oct 9;11(12):1343-1348. doi: 10.1016/j.hrcr.2025.09.015. eCollection 2025 Dec.NO ABSTRACTPMID:41550241 | PMC:PMC12805269 | DOI:10.1016/j.hrcr.2025.09.015
No abstractHeartRhythm Case Rep. 2025 Sep 18;11(12):1309-1314. doi: 10.1016/j.hrcr.2025.09.006. eCollection 2025 Dec.NO ABSTRACTPMID:41550211 | PMC:PMC12805295 | DOI:10.1016/j.hrcr.2025.09.006
Stem Cell Res. 2026 Mar;91:103910. doi: 10.1016/j.scr.2026.103910. Epub 2026 Jan 8.ABSTRACTThe GPD1L gene is located on 3p22.3. It encodes the glycerol phosphate dehydrogenase 1-like protein with homology to glycerol phosphate dehydrogenase (GPD1L), but the function of this enzyme is unclear. Mutati
Eur Heart J Case Rep. 2025 Dec 12;10(1):ytaf640. doi: 10.1093/ehjcr/ytaf640. eCollection 2026 Jan.ABSTRACTBACKGROUND: Brugada syndrome (BrS) is a rare cardiovascular condition that can lead to life-threatening arrhythmias. The SCN5A gene, most implicated in heritable BrS, is found in only 20% of tho
BMC Anesthesiol. 2026 Jan 13;26(1):101. doi: 10.1186/s12871-025-03600-2.ABSTRACTBACKGROUND: Brugada syndrome occurs typically without structural heart disease and is regarded as an autosomal dominant condition. It is linked to a range of cardiac symptoms as well as potentially fatal ventricular arrh
Egypt Heart J. 2026 Jan 12;78(1):4. doi: 10.1186/s43044-026-00714-x.ABSTRACTBACKGROUND: This cross-sectional study with limited prospective cohort follow-up aimed to determine the prevalence of Brugada-type ECG patterns (BTEPs) among asymptomatic Upper Egyptians using standard and high precordial le
