Circ J. 2026 Jan 20. doi: 10.1253/circj.CJ-25-0786. Online ahead of print.
ABSTRACT
BACKGROUND: In repaired tetralogy of Fallot (TOF) and related diseases, reoperation for pulmonary regurgitation (PR) may be delayed unless marked right ventricular (RV) enlargement is present.
METHODS AND RESULTS: 32 patients with significant PR post-repair underwent catheterization and 4D flow MRI for reoperation evaluation. The Non-severe RV Dilation group (n=20) did not meet the surgical volume criteria, whereas the Severe RV Dilation group (n=12) did. The Non-severe RV Dilation group had higher biventricular filling pressures. The RV-Energy loss index in both groups was high.
CONCLUSIONS: Diastolic dysfunction could serve as a therapeutic target in PR patients with heterogeneous etiologies.
PMID:41565290 | DOI:10.1253/circj.CJ-25-0786