Generation of an induced pluripotent stem cell line from a long QT syndrome type 1 patient carrying the KCNQ1 c.343G > A p.(E115K) variant
Long QT syndrome type 1 (LQT1) results from KCNQ1 mutations that compromise the slow delayed rectifier potassium current (I(Ks)), delaying cardiac repolarization, prolonging the QT interval, and increasing risk of life-threatening arrhythmias. LQT1 proarrhythmic risk is most often triggered by exerc
