Cureus. 2025 Dec 18;17(12):e99563. doi: 10.7759/cureus.99563. eCollection 2025 Dec.ABSTRACTConstrictive pericarditis (CP) is often misdiagnosed, making echocardiography essential for initial evaluation. We present a case of misdiagnosed constrictive pericarditis in a 66-year-old female with rheumato
Eur Heart J Case Rep. 2025 Dec 18;10(1):ytaf658. doi: 10.1093/ehjcr/ytaf658. eCollection 2026 Jan.ABSTRACTBACKGROUND: Paediatric acute ischaemic stroke (AIS) is a challenging diagnostic entity. A comprehensive cardiac evaluation is essential in all paediatric AIS cases to rule out cardioembolic sour
Rev Cardiovasc Med. 2025 Dec 24;26(12):46181. doi: 10.31083/RCM46181. eCollection 2025 Dec.ABSTRACTTransthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized and underdiagnosed cause of heart failure (HF), encompassing both preserved (HFpEF) and reduced (HFrEF) ejection fraction pheno
J Mol Cell Cardiol. 2026 Jan 4;212:26-37. doi: 10.1016/j.yjmcc.2026.01.001. Online ahead of print.ABSTRACTCardiac thin filament mutations in TNNI3 are associated with up to 3 % of hypertrophic (HCM) cardiomyopathy cases and contribute to severe restrictive (RCM) and dilated (DCM) cardiomyopathy case
J Clin Med. 2025 Dec 18;14(24):8963. doi: 10.3390/jcm14248963.ABSTRACTCardiac amyloidosis (CA) is an increasingly recognized cause of restrictive cardiomyopathy in which extracellular amyloid deposition leads to progressive structural and functional impairment. Beyond myocardial infiltration, growin
Diagnostics (Basel). 2025 Dec 5;15(24):3097. doi: 10.3390/diagnostics15243097.ABSTRACTBackground and Clinical Significance: FLNC encodes filamin C, a muscle-scaffolding protein crucial for cardiac integrity. Pathogenic FLNC variants cause diverse cardiomyopathies (hypertrophic, dilated, restrictive,
Genes Dis. 2025 Jul 25;13(2):101784. doi: 10.1016/j.gendis.2025.101784. eCollection 2026 Mar.ABSTRACTThis work aims to investigate the energy metabolism in mice with restrictive cardiomyopathy induced by cardiac troponin I (cTnI) R193H mutation. Echocardiography was used to monitor cardiac function.
J Cardiovasc Dev Dis. 2025 Dec 17;12(12):499. doi: 10.3390/jcdd12120499.ABSTRACTHypertrophic cardiomyopathy (HCM) progressing to end-stage heart failure and heart transplantation (HT) is a rare clinical scenario with an insufficiently explored genetic background. In this single-center retrospective
J Cardiovasc Dev Dis. 2025 Dec 12;12(12):492. doi: 10.3390/jcdd12120492.ABSTRACTThis study investigates FLNC mutations in Chinese cardiomyopathy patients. Background: Inherited cardiomyopathies, including dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RC
J Cardiovasc Dev Dis. 2025 Nov 29;12(12):466. doi: 10.3390/jcdd12120466.ABSTRACTThis study examines pediatric cardiomyopathies by analyzing genetic and clinical data from 55 patients (2021-2024) at Beijing Anzhen Hospital. Four subtypes were studied: dilated (DCM, 24), hypertrophic (HCM, 22), arrhyt
Cureus. 2025 Nov 12;17(11):e96651. doi: 10.7759/cureus.96651. eCollection 2025 Nov.ABSTRACTEndomyocardial fibrosis (EMF) is a neglected tropical cardiomyopathy, primarily affecting children and young adults in low-income equatorial regions. Characterized by fibrotic thickening of the ventricular end
Cardiovasc Diabetol Endocrinol Rep. 2025 Dec 15;11(1):40. doi: 10.1186/s40842-025-00252-6.ABSTRACTBACKGROUND: Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy characterized by progressive extracellular amyloid deposition, leading to restrictive heart failure (HF) and high morbidity. Diseas
J Feline Med Surg. 2025 Dec;27(12):1098612X251386638. doi: 10.1177/1098612X251386638. Epub 2025 Dec 12.ABSTRACTPRACTICAL RELEVANCE: Cardiomyopathies are a common condition and the leading cause of congestive heart failure (CHF) in cats; however, to date there have been limited therapeutic options av
Cureus. 2025 Nov 10;17(11):e96512. doi: 10.7759/cureus.96512. eCollection 2025 Nov.ABSTRACTCardiac amyloidosis is a cause of restrictive cardiomyopathy, posing significant challenges in perioperative care. We report the case of an 85-year-old male with wild-type transthyretin amyloidosis (ATTRwt) un
JACC Case Rep. 2025 Dec 11:106296. doi: 10.1016/j.jaccas.2025.106296. Online ahead of print.ABSTRACTBACKGROUND: Eosinophilic myocarditis and restrictive cardiomyopathy (Loeffler syndrome) are rare but severe manifestations of hypereosinophilic syndromes, especially in myeloid/lymphoid neoplasms with
Front Genet. 2025 Nov 26;16:1636999. doi: 10.3389/fgene.2025.1636999. eCollection 2025.ABSTRACTMyofibrillar myopathy is a cause of rare and severe pediatric cardiomyopathies. Few descriptions of patients carrying the rare p. Pro209Leu variant in BAG3 and presenting with myofibrillar myopathy are rep
Eur J Case Rep Intern Med. 2025 Nov 24;12(12):005878. doi: 10.12890/2025_005878. eCollection 2025.ABSTRACTAlthough rare globally, endomyocardial fibrosis (EMF) is the leading cause of restrictive cardiomyopathy in some tropical countries. However, its aetiology and pathogenesis remain unclear. Epide
No abstractHeartRhythm Case Rep. 2025 Jun 24;11(9):917-920. doi: 10.1016/j.hrcr.2025.06.022. eCollection 2025 Sep.NO ABSTRACTPMID:41333936 | PMC:PMC12666948 | DOI:10.1016/j.hrcr.2025.06.022
Biomolecules. 2025 Nov 9;15(11):1572. doi: 10.3390/biom15111572.ABSTRACTThe heart's relentless contractile activity depends critically on mitochondrial function to meet its extraordinary bioenergetic demands. Mitochondria, through oxidative phosphorylation, not only supply ATP but also regulate meta
J Cardiovasc Dev Dis. 2025 Oct 22;12(11):417. doi: 10.3390/jcdd12110417.ABSTRACTBACKGROUND: Wild-type transthyretin cardiac amyloidosis (ATTRwt-CM) is a frequent but underdiagnosed cause of heart failure with preserved ejection fraction (HFpEF) and left ventricular hypertrophy (LVH). Early identific
JACC Case Rep. 2025 Nov 19;30(37):105755. doi: 10.1016/j.jaccas.2025.105755.ABSTRACTBACKGROUND: Cardiac amyloidosis is a restrictive cardiomyopathy caused by myocardial deposition of insoluble amyloid fibrils. The 2 most frequent types are transthyretin amyloid cardiomyopathy (ATTR-CM) and light-cha
Front Cardiovasc Med. 2025 Oct 31;12:1636862. doi: 10.3389/fcvm.2025.1636862. eCollection 2025.ABSTRACTBACKGROUND: Fluid restriction is frequently recommended in heart failure (HF) management to prevent volume overload and improve clinical outcomes. However, the evidence supporting this practice rem
Eur Heart J Case Rep. 2025 Oct 23;9(11):ytaf541. doi: 10.1093/ehjcr/ytaf541. eCollection 2025 Nov.ABSTRACTBACKGROUND: Loeffler endocarditis is a cardiac disease characterized by infiltration of eosinophils in hypereosinophilic syndrome (HES), progressing through acute necrotic, thrombotic, and fibro
J Clin Med. 2025 Oct 22;14(21):7454. doi: 10.3390/jcm14217454.ABSTRACTThis comprehensive review explores the critical roles of microRNAs (miRNAS) in cardiovascular diseases, emphasizing their regulatory functions in gene expression and their involvement in disease progression. miRNAS are small, evol
