Curr Probl Cardiol. 2026 Sep 11:103455. doi: 10.1016/j.cpcardiol.2026.103455. Online ahead of print.ABSTRACTCardiac amyloidosis (CA) is an infiltrative cardiomyopathy caused by extracellular deposition of amyloid fibrils, most commonly derived from immunoglobulin light chains (AL) or transthyretin (
Eur J Radiol. 2026 Sep 6;205:113219. doi: 10.1016/j.ejrad.2026.113219. Online ahead of print.ABSTRACTBACKGROUND: Because the causes of left ventricular hypertrophy (LVH) share a thickened-wall phenotype yet demand divergent management, from transthyretin stabilization in cardiac amyloidosis (CA) to
Eur Heart J Case Rep. 2026 Sep 2;10(9):ytag662. doi: 10.1093/ehjcr/ytag662. eCollection 2026 Sep.ABSTRACTBACKGROUND: Thromboembolic complications are well recognized in cardiac amyloidosis and are traditionally attributed to atrial fibrillation (AF). However, patients with immunoglobulin light-chain
Clin Kidney J. 2026 Aug 18;19(9):sfag266. doi: 10.1093/ckj/sfag266. eCollection 2026 Sep.ABSTRACTCystic fibrosis transmembrane conductance regulator (CFTR) modulators have been revolutionary for cystic fibrosis patients. Their potential influence on AA amyloidosis has not been investigated. In AA am
Front Med (Lausanne). 2026 Aug 27;13:1882210. doi: 10.3389/fmed.2026.1882210. eCollection 2026.ABSTRACTBACKGROUND: Autonomic nervous system involvement is common in systemic amyloidosis, yet the clinical relevance of heart rate variability (HRV) in immunoglobulin light-chain (AL) amyloidosis remains
Eur J Neurosci. 2026 Sep;64(5):e70690. doi: 10.1111/ejn.70690.ABSTRACTTriggering receptor expressed on myeloid cells 2 (TREM2) is a key regulator of microglial and peripheral myeloid cell function, with its soluble form (sTREM2) emerging as a biomarker of neuroinflammation. Although cerebrospinal fl
Amyloid. 2026 Sep 10:1-12. doi: 10.1080/13506129.2026.2729446. Online ahead of print.ABSTRACTBACKGROUND: ATTR-CM is a multisystemic disease whose prevalence increases with age and contributes to the development of frailty. However, the prognostic value of frailty assessment in ATTR-CM remains poorly
Blood Res. 2026 Sep 10;61(1):52. doi: 10.1007/s44313-026-00174-x.ABSTRACTPURPOSE: Treatment of relapsed AL amyloidosis remains challenging as patients frequently suffer from severe organ dysfunctions. Daratumumab, a cornerstone drug in multiple myeloma and newly diagnosed AL amyloidosis, has also sh
JACC Adv. 2026 Sep 2:103200. doi: 10.1016/j.jacadv.2026.103200. Online ahead of print.ABSTRACTBACKGROUND: Diagnostic delay remains a major barrier to timely treatment in transthyretin amyloid cardiomyopathy (ATTR-CM). Although current approaches describe disease status at diagnosis, they do not capt
Gut Microbes. 2026 Dec 31;18(1):2728351. doi: 10.1080/19490976.2026.2728351. Epub 2026 Sep 10.ABSTRACTGut dysbiosis has been implicated in the pathogenesis of juvenile idiopathic arthritis (JIA), suggesting that microbiota-targeted interventions may influence immune signalling during early immune de
Ups J Med Sci. 2026 Jun 9;131. doi: 10.48101/ujms.v131.14458. eCollection 2026.ABSTRACTInterest in the misfolding and aggregation of human proteins into amyloid fibrils has increased dramatically in recent years. The systemic amyloidoses constitute a group of serious disorders that often affect the
Eur Heart J Digit Health. 2026 Sep 9;7(8):ztag140. doi: 10.1093/ehjdh/ztag140. eCollection 2026 Oct.ABSTRACTAIMS: Hypertrophic cardiomyopathy (HCM) remains underdiagnosed due to limited access to expert imaging. We developed and validated a deep-learning (DL)-based echocardiographic model adaptable
Circ Heart Fail. 2026 Sep 10:e012449. doi: 10.1161/CIRCHEARTFAILURE.125.012449. Online ahead of print.ABSTRACTBACKGROUND: Transthyretin cardiac amyloidosis (ATTR-CA) may involve heterogeneity in biological mechanisms (ie, molecular subtypes). Molecular subtypes potentially lead to differences in pro
Muscle Nerve. 2026 Sep 9. doi: 10.1002/mus.70394. Online ahead of print.ABSTRACTInherited peripheral neuropathies (IPNs) comprise a clinically and genetically heterogeneous group of disorders affecting approximately 1 in 2500 individuals and represent one of the most common inherited neurologic dise
Heart Fail Clin. 2026 Oct;22(4):463-475. doi: 10.1016/j.hfc.2026.07.007. Epub 2026 Aug 4.ABSTRACTThe interplay between cardiac and neurologic involvement in systemic amyloidosis is critical to understanding the full clinical burden of the disease. While cardiac involvement remains the most powerful
Biochem Biophys Res Commun. 2026 Sep 7;836:154561. doi: 10.1016/j.bbrc.2026.154561. Online ahead of print.ABSTRACTTransthyretin amyloidosis (ATTR) is caused by the deposition of transthyretin (TTR) aggregates. While unstable TTR monomers, which are dissociated from the native tetramer, are known to
Neurol Neuroimmunol Neuroinflamm. 2026 Nov;13(6):e200639. doi: 10.1212/NXI.0000000000200639. Epub 2026 Sep 9.ABSTRACTBACKGROUND AND OBJECTIVES: Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a potentially reversible inflammatory syndrome for which corticosteroid administration constitu
No abstractIndian Dermatol Online J. 2026 Sep 9. doi: 10.4103/idoj.idoj_343_26. Online ahead of print.NO ABSTRACTPMID:42714467 | DOI:10.4103/idoj.idoj_343_26
No abstractAm J Ther. 2026 Sep-Oct 01;33(5):e410-e413. doi: 10.1097/MJT.0000000000002141.NO ABSTRACTPMID:42714202 | DOI:10.1097/MJT.0000000000002141
No abstractIndian J Hematol Blood Transfus. 2026 Sep;42(5):2149-2151. doi: 10.1007/s12288-025-02268-5. Epub 2025 Dec 19.NO ABSTRACTPMID:42712654 | PMC:PMC13550250 | DOI:10.1007/s12288-025-02268-5
EXCLI J. 2026 Jul 17;25:1124-1170. doi: 10.17179/excli2026-9429. eCollection 2026.ABSTRACTType 1 diabetes (T1D), type 2 diabetes (T2D) and Alzheimer's disease (AD), which are heterogeneous multifactorial diseases, have become major global healthcare burdens and significant concerns for the future. H
Nat Neurosci. 2026 Sep 8. doi: 10.1038/s41593-026-02417-7. Online ahead of print.ABSTRACTBone marrow-derived macrophages were shown to play an important role in coping with Alzheimer's disease (AD). Boosting their spontaneous recruitment reduces inflammation and disease pathology and slows cognitive
JACC Adv. 2026 Sep 8;5(10 Pt 2):103211. doi: 10.1016/j.jacadv.2026.103211. Online ahead of print.ABSTRACTBACKGROUND: Early detection of cardiac involvement in light-chain (AL) amyloidosis remains challenging despite its prognostic importance. [18F]-florbetaben positron emission tomography/computed-t
Clin Nucl Med. 2026 Oct 1;51(10):908-910. doi: 10.1097/RLU.0000000000006624. Epub 2026 Aug 3.ABSTRACTScintigraphy using 99mTc-PYP as a bone-avid radiotracer reveals physiological and pathologic accumulation of the tracer in the extraosseous tissues and organs-including the breasts-in addition to the
