Alzheimers Dement. 2026 Sep;22(9):e71858. doi: 10.1002/alz.71858.ABSTRACTINTRODUCTION: Amyloid-beta (Aβ)-induced microvascular injury is a key pathological feature of cerebral amyloid angiopathy (CAA). Recent evidence suggests that ferroptosis is implicated in Aβ pathology; however, its cell-type sp
J Neurol. 2026 Sep 20;273(10):611. doi: 10.1007/s00415-026-14146-9.ABSTRACTBACKGROUND: Central nervous system (CNS) dysfunction is increasingly recognized in hereditary transthyretin (ATTRv) amyloidosis. We aimed to characterize CNS manifestations and assess associations with clinical variables and
Methodist Debakey Cardiovasc J. 2026 Sep 15;22(4):102-105. doi: 10.14797/mdcvj.1955. eCollection 2026.ABSTRACTGenetic testing is the step most often omitted once a cardiomyopathy has been characterized and the step most often misapplied when it is extended to people who have no phenotype. I describe
Case Rep Nephrol. 2026 Sep 18;2026:3992146. doi: 10.1155/crin/3992146. eCollection 2026.ABSTRACTBACKGROUND: Tuberculosis (TB) is highly prevalent in Ethiopia, and extrapulmonary manifestations pose significant diagnostic challenges. Among its rare complications, renal amyloidosis (AA type) can prese
Cardiol Res Pract. 2026 Sep 17;2026:3289574. doi: 10.1155/crp/3289574. eCollection 2026.ABSTRACTBACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) remains under-recognised, and earlier identification is increasingly important with disease-modifying therapy. Artificial intelligence (AI) appli
bioRxiv [Preprint]. 2026 Aug 28:2026.08.24.746819. doi: 10.64898/2026.08.24.746819.ABSTRACTImmunoglobulin light chain (LC) amyloidosis is a debilitating multiorgan disease with limited treatment options. Sequence and structural variability make LC amyloids particularly challenging for therapeutic ta
J Clin Rheumatol. 2026 Sep 17. doi: 10.1097/RHU.0000000000002402. Online ahead of print.ABSTRACTOBJECTIVES: Still disease, which includes systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still disease (AOSD), has historically had age-related treatment differences. With the advent of bDM
No abstractJ Cutan Med Surg. 2026 Sep 18:12034754261488367. doi: 10.1177/12034754261488367. Online ahead of print.NO ABSTRACTPMID:42757764 | DOI:10.1177/12034754261488367
Medeni Med J. 2026 Sep 18;41(3):359-364. doi: 10.4274/MMJ.galenos.2026.87036.ABSTRACTWe report a 72-year-old man with long-standing hypertension, type 2 diabetes, and ischemic heart disease, in whom autopsy, following a fatal acute coronary syndrome, revealed marked cardiomegaly (heart weight, 911 g
J Formos Med Assoc. 2026 Sep 17:S0929-6646(26)00906-X. doi: 10.1016/j.jfma.2026.09.021. Online ahead of print.ABSTRACTBACKGROUND: Cardiac involvement is a common presentation of late-onset hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN). This study explored phenotypes of cardiac
Int J Cardiol. 2026 Sep 17:134787. doi: 10.1016/j.ijcard.2026.134787. Online ahead of print.ABSTRACTINTRODUCTION AND OBJECTIVES: Transthyretin cardiac amyloidosis (ATTR-CA) is more prevalent among patients with severe aortic stenosis (AS). The RAISE score was developed to facilitate early identifica
Clin Rheumatol. 2026 Sep 17. doi: 10.1007/s10067-026-08422-2. Online ahead of print.ABSTRACTINTRODUCTION: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by entheseal inflammation, pathological new bone formation and structural lesions on spinal radiography. Chronic k
JACC Case Rep. 2026 Sep 16;31(37):110259. doi: 10.1016/j.jaccas.2026.110259. Epub 2026 Sep 16.ABSTRACTBACKGROUND: Variant transthyretin amyloidosis (ATTRv) is an underdiagnosed cause of heart failure (HF), typically identified at later disease stages. The TTR p.Val142Ile (V142I) variant, found in ∼4
Respirol Case Rep. 2026 Sep 15;14(9):e70757. doi: 10.1002/rcr2.70757. eCollection 2026 Sep.ABSTRACTPulmonary amyloidosis is a rare disease with diverse radiological manifestations that may mimic malignancy or diffuse interstitial lung disease. Although conventional forceps transbronchial lung biopsy
Neurol Sci. 2026 Sep 17;47(10):792. doi: 10.1007/s10072-026-09395-5.ABSTRACTBACKGROUND: Presymptomatic genetic testing in relatives of hereditary transthyretin amyloidosis (ATTRv) index cases enables early carrier identification and timely treatment, but a confirmed pathogenic variant carries the ri
No abstractHeart. 2026 Sep 16:heartjnl-2026-328728. doi: 10.1136/heartjnl-2026-328728. Online ahead of print.NO ABSTRACTPMID:42749476 | DOI:10.1136/heartjnl-2026-328728
Echocardiography. 2026 Sep;43(9):e70625. doi: 10.1111/echo.70625.ABSTRACTBACKGROUND: In wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM), increased left ventricular wall thickness reflects amyloid infiltration rather than myocyte hypertrophy, and QRS voltage may not rise proportionally. Wh
Leuk Lymphoma. 2026 Sep 16:1-12. doi: 10.1080/10428194.2026.2728612. Online ahead of print.ABSTRACTHHV8-positive diffuse large B-cell lymphoma (HHV8+ DLBCL) is a rare and aggressive lymphoma frequently associated with multicentric Castleman disease. Population-based data remain limited. Using the Na
Front Immunol. 2026 Sep 1;17:1932951. doi: 10.3389/fimmu.2026.1932951. eCollection 2026.ABSTRACTAnti-CD38 monoclonal antibodies have become a central immunotherapeutic platform in multiple myeloma, where they have reshaped treatment across relapsed or refractory disease, frontline therapy, maintenan
Clin Kidney J. 2026 Aug 29;19(9):sfag293. doi: 10.1093/ckj/sfag293. eCollection 2026 Sep.ABSTRACTBACKGROUND: The disease spectrum of intratubular light chain amyloidosis (AL) remains unknown.METHODS: Patients with intratubular AL from a single center were retrospectively analyzed and stratified into
Perm J. 2026 Sep 16:1-10. doi: 10.7812/TPP/26.065. Online ahead of print.ABSTRACTINTRODUCTION: Artificial intelligence (AI) holds tremendous promise to improve clinical decision-making across diagnosis, risk assessment, and patient care. However, most prior work has focused on model development in c
Muscle Nerve. 2026 Sep 15. doi: 10.1002/mus.70406. Online ahead of print.ABSTRACTINTRODUCTION/AIMS: Transthyretin (TTR) stabilizers and gene-silencing therapies are approved for hereditary transthyretin-mediated amyloidosis with polyneuropathy (ATTRv-PN), but data from clinical practice in patients
Turk J Haematol. 2026 Sep 16. doi: 10.4274/tjh.galenos.2026.79353. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to characterize the inflammatory and complication profiles of patients with retroperitoneal unicentric Castleman disease (UCD), compare the clinical features of UCD with an MCD-like i
No abstractHeart. 2026 Sep 15:heartjnl-2026-328899. doi: 10.1136/heartjnl-2026-328899. Online ahead of print.NO ABSTRACTPMID:42744604 | DOI:10.1136/heartjnl-2026-328899
